OR51A7

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR51A7 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR51A7-associated genes across cancer lineages are OR10G3, ARSH, and GAGE12H. Each is linked with OR51A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51A7-to-partner and partner-to-OR51A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10G3 grouped by OR51A7-low versus OR51A7-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51A7→partner) and Y-score (partner→OR51A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaOR10G3 →+0.035+5.201<.001.00631
BLOOD_LeukemiaARSH →+0.012+4.922<.001.00931
BLOOD_LeukemiaGAGE12H →+0.947+4.922<.001.00931
BLOOD_LeukemiaPRR20C →+0.026+5.539<.001.00331
BLOOD_LeukemiaOR1D5 →+0.032+5.969<.001.00131
LARGE_INTESTINETTLL8 →+0.002+3.700<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

OR10G3 by OR51A7 expression — BLOOD_Leukemia

Box plot of OR10G3 in OR51A7-low vs OR51A7-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration