OR4S2

Across TCGA cell cohorts, OR4S2 RNA expression is significantly associated with the mutation status of many other genes, with 56 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible OR4S2-associated genes across cancer lineages are ST14, XRN2, and EXPH5. Each is linked with OR4S2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4S2-to-partner and partner-to-OR4S2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ST14 grouped by OR4S2-low versus OR4S2-high in PANCREAS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4S2→partner) and Y-score (partner→OR4S2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	ST14 →	+4.029	+0.013	.007	<.001	3	1
LUNG_NSCLC_LUSC	XRN2 →	+4.643	+0.086	.008	.001	3	1
LUNG_NSCLC_LUSC	EXPH5 →	+4.643	+0.086	.008	.001	3	1
LUNG_NSCLC_LUSC	CHD5 →	+4.643	+0.086	.008	.001	3	1
SKIN	HR →	+4.022	+0.021	.006	<.001	3	1
SKIN	NDNF →	+4.022	+0.021	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

ST14 by OR4S2 expression — PANCREAS

Explore this box plot interactively →