OR4P4

Across TCGA patient cohorts, OR4P4 mutation is significantly associated with the RNA expression of many other genes, with 2,460 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR4P4-associated genes across cancer lineages are VDAC1, ETF1, and SNRPGP19. Each is linked with OR4P4 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR4P4-to-partner and partner-to-OR4P4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VDAC1 grouped by OR4P4-low versus OR4P4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4P4→partner) and Y-score (partner→OR4P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VDAC1 →	+0.494	+2.923	.001	<.001	3	3
UCEC	ETF1 →	+0.428	+1.776	.006	.008	3	3
HNSC	SNRPGP19 →	+0.208	+4.754	<.001	.005	3	3
SKCM	CRADD →	+0.673	+3.506	.001	.002	3	3
UCEC	AP3D1 →	+0.574	+2.662	<.001	<.001	3	3
UCEC	CBARP →	+0.545	+2.329	.003	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,460 associations by consensus.

VDAC1 by OR4P4 expression — UCEC

Explore this box plot interactively →