OR4P4

Across TCGA cell cohorts, OR4P4 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible OR4P4-associated genes across cancer lineages are ZNF735, SPATA19, and PRSS38. Each is linked with OR4P4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4P4-to-partner and partner-to-OR4P4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF735 grouped by OR4P4-low versus OR4P4-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4P4→partner) and Y-score (partner→OR4P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	ZNF735 →	+0.050	+4.044	<.001	.009	3	1
STOMACH	SPATA19 →	+0.167	+3.209	.008	.007	3	1
STOMACH	PRSS38 →	+0.010	+3.209	.001	.007	3	1
STOMACH	IGFL3 →	+0.444	+4.009	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

ZNF735 by OR4P4 expression — LUNG_SCLC

Explore this box plot interactively →