Across TCGA patient cohorts, OR4N4 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible OR4N4-associated genes across cancer lineages are UBE2Q2P9, MIR890, and ALDH7A1P4. Each is linked with OR4N4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4N4-to-partner and partner-to-OR4N4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4N4→partner) and Y-score (partner→OR4N4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	UBE2Q2P9 →	+1.426	+5.362	<.001	.005	3	2
BRCA	MIR890 →	+0.462	+8.471	<.001	.005	3	2
LUAD	ALDH7A1P4 →	+0.200	+5.584	<.001	.002	3	2
BRCA	RNU6-765P →	+0.381	+7.731	<.001	.009	3	1
SKCM	CTBP2P9 →	+0.054	+6.080	<.001	.002	3	1
LUAD	MIR206 →	+0.435	+6.924	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

OR4N4 survival (RNA) · tumor vs normal (RNA) · all OR4N4 data types