Across TCGA pan-cancer cohorts, OR4N4 RNA is linked to patient survival in 1 of 34 cancer types, making it a survival-associated OR4N4 data layer compared with 5 for mutation status.
The strongest signal is observed in lung adenocarcinoma (LUAD), where higher OR4N4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR4N4 expression acts as an unfavorable survival marker.
LUAD are the cancer types where OR4N4 RNA most reproducibly stratifies survival.