Across TCGA cell cohorts, OR4N4 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR4N4-associated genes across cancer lineages are KRTAP6-1, ZP4, and OR10J5. Each is linked with OR4N4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4N4-to-partner and partner-to-OR4N4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4N4→partner) and Y-score (partner→OR4N4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	KRTAP6-1 →	+0.075	+5.022	<.001	.002	3	2
LUNG_SCLC	ZP4 →	+0.013	+5.643	<.001	.002	3	1
SKIN	OR10J5 →	+0.020	+5.022	<.001	.002	3	1
SKIN	NPS →	+0.330	+4.415	<.001	.007	3	1
LUNG_NSCLC_LUAD	PPY →	+0.058	+3.734	<.001	.006	3	1
LUNG_NSCLC_LUAD	MS4A10 →	+0.495	+3.544	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

OR4N4 survival (RNA) · tumor vs normal (RNA) · all OR4N4 data types