OR4M1

Across TCGA patient cohorts, OR4M1 mutation is significantly associated with the RNA expression of many other genes, with 1,293 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible OR4M1-associated genes across cancer lineages are CKS1BP6, PSAT1P4, and RPS2P18. Each is linked with OR4M1 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR4M1-to-partner and partner-to-OR4M1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CKS1BP6 grouped by OR4M1-low versus OR4M1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4M1→partner) and Y-score (partner→OR4M1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CKS1BP6 →	+0.106	+1.418	.006	.005	3	4
COAD	PSAT1P4 →	+0.545	+3.463	<.001	.006	3	3
BLCA	RPS2P18 →	+0.082	+4.048	.008	.002	3	3
BLCA	RPL22P20 →	+0.255	+4.213	<.001	.001	3	3
BRCA	RNA5SP416 →	+0.669	+7.471	<.001	.008	3	3
LUAD	VPS25P1 →	+0.200	+2.577	<.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,293 associations by consensus.

CKS1BP6 by OR4M1 expression — SKCM

Explore this box plot interactively →