OR4M1

Across TCGA cell cohorts, OR4M1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR4M1-associated genes across cancer lineages are OR52W1, SLC25A31, and FAM90A26. Each is linked with OR4M1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4M1-to-partner and partner-to-OR4M1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52W1 grouped by OR4M1-low versus OR4M1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4M1→partner) and Y-score (partner→OR4M1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR52W1 →	+0.064	+4.000	<.001	.004	3	1
LUNG_NSCLC_LUAD	SLC25A31 →	+0.015	+4.058	.001	.003	3	1
LUNG_NSCLC_LUAD	FAM90A26 →	+0.017	+4.803	<.001	<.001	3	1
LARGE_INTESTINE	BRDT →	+0.080	+2.906	<.001	.007	3	1
LARGE_INTESTINE	MCHR2 →	+0.014	+2.777	.001	.004	3	1
LARGE_INTESTINE	OR2T8 →	+0.126	+2.956	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

OR52W1 by OR4M1 expression — SKIN

Explore this box plot interactively →