OR4K5

Across TCGA cell cohorts, OR4K5 RNA expression is significantly associated with the mutation status of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR4K5-associated genes across cancer lineages are SPEM2, ZNF737, and PPIP5K2. Each is linked with OR4K5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4K5-to-partner and partner-to-OR4K5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPEM2 grouped by OR4K5-low versus OR4K5-high in BLOOD_Leukemia.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4K5→partner) and Y-score (partner→OR4K5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SPEM2 →	+3.969	+0.044	.009	<.001	3	1
BLOOD_Leukemia	ZNF737 →	+4.384	+0.053	.006	<.001	3	1
LUNG_NSCLC_LUAD	PPIP5K2 →	+3.944	+0.008	.006	<.001	3	1
LUNG_NSCLC_LUAD	ASAP1 →	+4.266	+0.010	.004	<.001	3	1
LUNG_NSCLC_LUAD	GALNT14 →	+5.266	+0.015	.001	<.001	3	1
LUNG_NSCLC_LUAD	GANC →	+5.266	+0.015	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

SPEM2 by OR4K5 expression — BLOOD_Leukemia

Explore this box plot interactively →