OR4K5

Across TCGA pan-cancer cohorts, OR4K5 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated OR4K5 data layer compared with 2 for mutation status.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher OR4K5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR4K5 expression acts as an unfavorable survival marker.

BLCA, COAD, and SCLC are the cancer types where OR4K5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.156	0.629	<.001	90	view →
COAD	OS	Tertile	II,III,IV	0.377	0.796	.001	45	view →
SCLC	OS	Tertile	All	0.055	0.708	<.001	36	view →
UVM	OS	Tertile	All	0.249	0.712	.033	18	view →
KIRP	DFS	Tertile	II,III,IV	0.157	0.686	.031	18	view →
UCEC	DFS	Tertile	All	0.826	0.899	.022	12	view →
ESCA	OS	Tertile	All	0.470	0.906	.017	9	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

OR4K5–BLCA (DFS)

Open the BLCA breakdown →