OR4K15

Across TCGA patient cohorts, OR4K15 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR4K15-associated genes across cancer lineages are Rab25, FoxM1, and PRAS40_pT246. Each is linked with OR4K15 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR4K15-to-partner and partner-to-OR4K15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rab25 grouped by OR4K15-low versus OR4K15-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4K15→partner) and Y-score (partner→OR4K15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rab25 →	-0.448	-3.584	.001	.002	3	2
UCEC	FoxM1 →	+0.292	+2.321	.006	.006	3	2
UCEC	PRAS40_pT246 →	+0.198	+1.820	.005	.016	3	2
UCEC	Annexin_VII →	-0.124	-2.990	.030	.036	3	2
LUAD	p90 RSK →	-0.286	-3.000	.032	.036	2	2
LUAD	ASNS →	+0.619	+3.000	.015	.036	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Rab25 by OR4K15 expression — UCEC

Explore this box plot interactively →