OR4K15

Across TCGA pan-cancer cohorts, OR4K15 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated OR4K15 data layer compared with 7 for mutation status.

The strongest signal is observed in small cell lung cancer (SCLC), where higher OR4K15 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR4K15 expression acts as an unfavorable survival marker.

SCLC, LUAD, and KIRP are the cancer types where OR4K15 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	DFS	Tertile	II,III,IV	0.247	0.797	.016	36	view →
LUAD	OS	Tertile	All	0.649	0.836	.025	24	view →
KIRP	OS	Tertile	All	0.287	0.714	.016	24	view →
CESC	OS	Tertile	III,IV	0.167	0.657	.044	18	view →
SARC	OS	Tertile	All	0.430	0.865	.004	15	view →
UCEC	OS	Tertile	All	0.899	0.927	.018	12	view →
STAD	OS	Tertile	All	0.263	0.454	.048	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

OR4K15–SCLC (DFS)

Open the SCLC breakdown →