OR4K15

Across TCGA cell cohorts, OR4K15 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR4K15-associated genes across cancer lineages are KLHL40, OR10W1, and OR52H1. Each is linked with OR4K15 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4K15-to-partner and partner-to-OR4K15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KLHL40 grouped by OR4K15-low versus OR4K15-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4K15→partner) and Y-score (partner→OR4K15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	KLHL40 →	+0.006	+4.273	<.001	.006	3	1
LARGE_INTESTINE	OR10W1 →	+0.012	+3.977	<.001	.001	3	1
LARGE_INTESTINE	OR52H1 →	+0.027	+3.347	<.001	.005	3	1
LARGE_INTESTINE	KIR2DS4 →	+0.007	+3.345	<.001	.007	3	1
LUNG_SCLC	MAGEB4 →	+0.004	+4.058	<.001	.007	3	1
LARGE_INTESTINE	NAT8 →	+0.718	+3.443	<.001	.009	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

KLHL40 by OR4K15 expression — SKIN

Explore this box plot interactively →