OR4K14

Across TCGA pan-cancer cohorts, OR4K14 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated OR4K14 data layer compared with 10 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher OR4K14 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR4K14 expression acts as an unfavorable survival marker.

COAD, LUSC, and LIHC are the cancer types where OR4K14 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	III,IV	0.140	0.792	<.001	15	view →
LUSC	OS	Median	III,IV	0.268	0.583	.021	14	view →
LIHC	OS	Median	All	0.118	0.783	<.001	12	view →
CESC	OS	Median	All	0.099	0.585	.049	6	view →
STAD	OS	Median	All	0.187	0.667	.015	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

OR4K14–COAD (OS)

Open the COAD breakdown →