OR4K13

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR4K13 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR4K13-associated genes across cancer lineages are USP17L18, HTR3D, and RBMY1D. Each is linked with OR4K13 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4K13-to-partner and partner-to-OR4K13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP17L18 grouped by OR4K13-low versus OR4K13-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4K13→partner) and Y-score (partner→OR4K13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaUSP17L18 →+0.004+4.539<.001.00732
BLOOD_LeukemiaHTR3D →+0.014+4.539<.001.00731
BLOOD_LeukemiaRBMY1D →+0.134+4.539<.001.00731
BLOOD_LeukemiaUSP17L20 →+0.004+4.539<.001.00731
BLOOD_LeukemiaKRTAP7-1 →+0.079+4.539<.001.00731
BLOOD_LeukemiaCT45A6 →+0.188+5.507<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

USP17L18 by OR4K13 expression — BLOOD_Leukemia

Box plot of USP17L18 in OR4K13-low vs OR4K13-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration