OR4D9

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR4D9 mutation is significantly associated with the RNA expression of many other genes, with 244 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR4D9-associated genes across cancer lineages are SMIM11P1, MIR629, and RNU6-113P. Each is linked with OR4D9 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4D9-to-partner and partner-to-OR4D9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMIM11P1 grouped by OR4D9-low versus OR4D9-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4D9→partner) and Y-score (partner→OR4D9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCASMIM11P1 →+0.266+5.251<.001.00632
LUADMIR629 →+0.318+3.363<.001.00632
LUADRNU6-113P →+0.186+6.345<.001<.00132
LUADMIR4300 →+0.253+5.014<.001.00232
SKCMSNORA13 →-0.616-2.690<.001.00632
BLCAOOSP1P1 →+0.182+5.685.002.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 244 associations by consensus.

SMIM11P1 by OR4D9 expression — BLCA

Box plot of SMIM11P1 in OR4D9-low vs OR4D9-high samples in BLCA.

Explore this box plot interactively →

Exploration