OR4D2

Across TCGA cell cohorts, OR4D2 RNA expression is significantly associated with the mutation status of many other genes, with 83 significant associations in total. CNS shows the largest number of these associations.

The most reproducible OR4D2-associated genes across cancer lineages are SLC8A1, TNFRSF25, and KMT2A. Each is linked with OR4D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4D2-to-partner and partner-to-OR4D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC8A1 grouped by OR4D2-low versus OR4D2-high in BLOOD_Myeloma.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4D2→partner) and Y-score (partner→OR4D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	SLC8A1 →	+4.807	+0.013	.006	<.001	3	2
BLOOD_Myeloma	TNFRSF25 →	+4.807	+0.013	.006	<.001	3	2
OESOPHAGUS	KMT2A →	+3.273	+0.015	.004	<.001	3	2
BLOOD_Leukemia	OR10G2 →	+5.569	+0.012	.001	<.001	3	2
CNS	GRIN2B →	+4.772	+0.012	.002	<.001	3	2
CNS	CHAT →	+5.357	+0.015	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 83 associations by consensus.

SLC8A1 by OR4D2 expression — BLOOD_Myeloma

Explore this box plot interactively →