OR4D2

Across TCGA cell cohorts, OR4D2 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR4D2-associated genes across cancer lineages are OR10W1, OR10Q1, and OR52A1. Each is linked with OR4D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4D2-to-partner and partner-to-OR4D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by OR4D2-low versus OR4D2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4D2→partner) and Y-score (partner→OR4D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR10W1 →	+0.016	+3.977	<.001	.001	3	1
LARGE_INTESTINE	OR10Q1 →	+0.095	+4.242	.002	.001	3	1
LARGE_INTESTINE	OR52A1 →	+0.008	+3.347	<.001	.005	3	1
LARGE_INTESTINE	LCE2A →	+0.101	+3.632	<.001	.003	3	1
LARGE_INTESTINE	GAGE12H →	+0.055	+4.022	<.001	.006	3	1
LARGE_INTESTINE	GMCL2 →	+0.055	+3.428	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

OR10W1 by OR4D2 expression — LARGE_INTESTINE

Explore this box plot interactively →