OR4D11

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR4D11 mutation is significantly associated with the RNA expression of many other genes, with 937 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR4D11-associated genes across cancer lineages are UBE2S, MIR4790, and ZMYND19. Each is linked with OR4D11 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR4D11-to-partner and partner-to-OR4D11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBE2S grouped by OR4D11-low versus OR4D11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4D11→partner) and Y-score (partner→OR4D11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECUBE2S →+0.780+3.191.004.00933
STADMIR4790 →+1.043+4.363<.001.00733
SKCMZMYND19 →+0.369+2.341.009.00333
UCECMIR7702 →+0.245+4.360<.001.00432
HNSCRPL23AP39 →+0.141+5.241<.001.00732
UCECSSU72 →+0.367+3.370.003.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 937 associations by consensus.

UBE2S by OR4D11 expression — UCEC

Box plot of UBE2S in OR4D11-low vs OR4D11-high samples in UCEC.

Explore this box plot interactively →

Exploration