OR4D11

Across TCGA pan-cancer cohorts, OR4D11 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated OR4D11 data layer compared with 5 for mutation status.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher OR4D11 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR4D11 expression acts as an unfavorable survival marker.

DLBC, THYM, and KIRC are the cancer types where OR4D11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	DFS	Tertile	All	0.338	0.813	.003	88	view →
THYM	DFS	Tertile	All	0.091	0.884	<.001	36	view →
KIRC	DFS	Tertile	III,IV	0.414	0.670	.015	36	view →
SKCM	OS	Tertile	III,IV	0.118	0.393	.011	33	view →
BLCA	DFS	Tertile	III,IV	0.193	0.576	.004	27	view →
SCLC	DFS	Tertile	All	0.228	0.697	.008	24	view →
CESC	OS	Tertile	II,III,IV	0.203	0.759	.021	18	view →
ESCA	DFS	Tertile	All	0.148	0.673	.040	18	view →
PAAD	OS	Tertile	All	0.232	0.594	.011	18	view →
LUSC	OS	Tertile	II,III,IV	0.073	0.733	<.001	18	view →
THCA	DFS	Tertile	II,III,IV	0.743	0.928	.015	12	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

OR4D11–DLBC (DFS)

Open the DLBC breakdown →