OR4D11

Across TCGA cell cohorts, OR4D11 mutation is significantly associated with the mutation status of many other genes, with 2,268 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR4D11-associated genes across cancer lineages are GAB3, MAP3K15, and ZNF100. Each is linked with OR4D11 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR4D11-to-partner and partner-to-OR4D11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAB3 grouped by OR4D11-low versus OR4D11-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4D11→partner) and Y-score (partner→OR4D11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GAB3 →	+3.894	+5.247	.001	.001	1	4
BLOOD_Leukemia	MAP3K15 →	+3.672	+5.083	.001	.001	1	3
LARGE_INTESTINE	ZNF100 →	+3.087	+4.392	.005	.005	1	3
BLOOD_Leukemia	OR1J2 →	+5.894	+5.321	.002	.002	1	3
BLOOD_Leukemia	ANKRD17 →	+2.894	+4.432	.005	.005	1	3
BLOOD_Leukemia	ANO3 →	+3.309	+4.794	.002	.002	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,268 associations by consensus.

GAB3 by OR4D11 expression — BLOOD_Leukemia

Explore this box plot interactively →