OR4C6

Across TCGA patient cohorts, OR4C6 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,980 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible OR4C6-associated GO terms across cancer lineages are B cell mediated immunity, Tumor necrosis factor superfamily cytokine production, and Myeloid leukocyte activation. Each is linked with OR4C6 in more than 16 cancer types. Because this analysis shows association rather than direction, both OR4C6-to-partner and partner-to-OR4C6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell mediated immunity grouped by OR4C6-low versus OR4C6-high in THCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C6→partner) and Y-score (partner→OR4C6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	B cell mediated immunity →	+0.105	+0.060	<.001	<.001	3	17
SCLC	Tumor necrosis factor superfamily cytokine production →	+0.097	+0.126	<.001	.007	3	16
SCLC	Myeloid leukocyte activation →	+0.094	+0.134	<.001	.005	3	15
THCA	Immunoglobulin production →	+0.072	+0.060	<.001	<.001	3	15
LAML	Negative regulation of immune response →	+0.038	+0.040	.001	.001	2	16
SCLC	Negative regulation of lymphocyte activation →	+0.079	+0.118	.003	.007	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,980 associations by consensus.

B cell mediated immunity by OR4C6 expression — THCA

Explore this box plot interactively →