OR4C6

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR4C6 RNA expression is significantly associated with the go_rna of many other GO terms, with 452 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible OR4C6-associated GO terms across cancer lineages are Positive regulation of protein localization to lysosome, Negative regulation of defense response, and Negative regulation of catalytic activity. Each is linked with OR4C6 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR4C6-to-partner and partner-to-OR4C6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein localization to lysosome grouped by OR4C6-low versus OR4C6-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C6→partner) and Y-score (partner→OR4C6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASPositive regulation of protein localization to lysosome →+0.144+0.556<.001.00433
PANCREASNegative regulation of defense response →+0.058+0.645.002.00833
PANCREASNegative regulation of catalytic activity →+0.046+0.449<.001.00533
BLOOD_LymphomaUridine metabolic process →+0.636+0.181.004.00833
BLOOD_LymphomaPyrimidine ribonucleoside metabolic process →+0.636+0.181.004.00833
LUNG_NSCLC_LUADRegulation of keratinocyte proliferation →+0.072+0.483<.001.00433
Each partner links to its Q-omics profile. Showing the 6 strongest of 452 associations by consensus.

Positive regulation of protein localization to lysosome by OR4C6 expression — PANCREAS

Box plot of Positive regulation of protein localization to lysosome in OR4C6-low vs OR4C6-high samples in PANCREAS.

Explore this box plot interactively →

Exploration