OR4C6

Across TCGA cell cohorts, OR4C6 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR4C6-associated genes across cancer lineages are CNGA2, MYF6, and USP17L17. Each is linked with OR4C6 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4C6-to-partner and partner-to-OR4C6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CNGA2 grouped by OR4C6-low versus OR4C6-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C6→partner) and Y-score (partner→OR4C6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	CNGA2 →	+0.005	+3.392	<.001	.007	3	1
STOMACH	MYF6 →	+0.013	+5.285	<.001	.003	3	1
STOMACH	USP17L17 →	+0.013	+5.285	<.001	.003	3	1
LUNG_NSCLC_LUAD	ZNF503 →	+1.126	+3.358	.007	.003	3	1
LUNG_NSCLC_LUAD	MTMR10 →	-0.589	-3.321	.001	.004	3	1
LUNG_NSCLC_LUAD	RPS4X →	+0.615	+3.358	.006	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

CNGA2 by OR4C6 expression — OESOPHAGUS

Explore this box plot interactively →