OR4C45

Across TCGA cell cohorts, OR4C45 RNA expression is significantly associated with the mutation status of many other genes, with 12 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible OR4C45-associated genes across cancer lineages are TSC2, PPP6R1, and AVIL. Each is linked with OR4C45 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4C45-to-partner and partner-to-OR4C45 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSC2 grouped by OR4C45-low versus OR4C45-high in BREAST.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C45→partner) and Y-score (partner→OR4C45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	TSC2 →	+3.781	+0.011	.009	<.001	3	1
BREAST	PPP6R1 →	+4.196	+0.014	.006	<.001	3	1
BREAST	AVIL →	+4.781	+0.017	.003	<.001	3	1
BREAST	ASXL3 →	+5.781	+0.023	.001	<.001	3	1
BREAST	TOR1AIP1 →	+4.781	+0.017	.003	<.001	3	1
BREAST	NDST3 →	+4.781	+0.017	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

TSC2 by OR4C45 expression — BREAST

Explore this box plot interactively →