OR4C13

Across TCGA patient cohorts, OR4C13 mutation is significantly associated with the RNA expression of many other genes, with 2,032 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR4C13-associated genes across cancer lineages are CHAF1A, TMEM120B, and KIF4B. Each is linked with OR4C13 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR4C13-to-partner and partner-to-OR4C13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHAF1A grouped by OR4C13-low versus OR4C13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C13→partner) and Y-score (partner→OR4C13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CHAF1A →	+0.703	+2.191	<.001	<.001	3	3
SKCM	TMEM120B →	+0.252	+2.260	.007	.005	3	3
SKCM	KIF4B →	+0.028	+1.919	.001	<.001	3	3
UCEC	MYO19 →	+0.465	+1.893	<.001	<.001	3	3
UCEC	LIG1 →	+0.484	+2.545	<.001	<.001	3	3
LUSC	VNN1 →	-0.822	-3.447	.006	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,032 associations by consensus.

CHAF1A by OR4C13 expression — UCEC

Explore this box plot interactively →