OR4C13

Across TCGA patient cohorts, OR4C13 mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR4C13-associated genes across cancer lineages are NDRG1_pT346, PREX1, and GAPDH. Each is linked with OR4C13 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4C13-to-partner and partner-to-OR4C13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NDRG1_pT346 grouped by OR4C13-low versus OR4C13-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C13→partner) and Y-score (partner→OR4C13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	NDRG1_pT346 →	+0.732	+3.000	.043	.035	3	2
LUSC	PREX1 →	-0.216	-3.445	.006	.005	3	2
UCEC	GAPDH →	+0.429	+2.222	.019	.010	3	2
UCEC	ACC1 →	+0.318	+1.820	.010	.014	3	2
UCEC	Rictor_pT1135 →	-0.092	-1.247	.008	.045	3	2
UCEC	Snail →	-0.224	-2.321	.040	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

NDRG1_pT346 by OR4C13 expression — LUSC

Explore this box plot interactively →