OR4C13

Across TCGA cell cohorts, OR4C13 RNA expression is significantly associated with the mutation status of many other genes, with 7 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible OR4C13-associated genes across cancer lineages are ARHGAP22, MDC1, and ZNF618. Each is linked with OR4C13 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4C13-to-partner and partner-to-OR4C13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARHGAP22 grouped by OR4C13-low versus OR4C13-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C13→partner) and Y-score (partner→OR4C13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	ARHGAP22 →	+5.357	+0.073	.003	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	MDC1 →	+4.357	+0.055	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	ZNF618 →	+4.357	+0.055	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	ZNF770 →	+4.357	+0.055	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	KLHL23 →	+5.357	+0.073	.003	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	ZNF658 →	+4.357	+0.055	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

ARHGAP22 by OR4C13 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →