OR4C13

Across TCGA cell cohorts, OR4C13 mutation is significantly associated with the RNA expression of many other genes, with 49 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR4C13-associated genes across cancer lineages are AMELX, TCF21, and TSHB. Each is linked with OR4C13 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4C13-to-partner and partner-to-OR4C13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AMELX grouped by OR4C13-low versus OR4C13-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C13→partner) and Y-score (partner→OR4C13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	AMELX →	+0.028	+4.539	<.001	.007	3	2
BLOOD_Leukemia	TCF21 →	+0.013	+4.705	<.001	.003	3	1
BLOOD_Leukemia	TSHB →	+0.235	+4.276	<.001	.007	3	1
BLOOD_Leukemia	LRIT1 →	+0.054	+5.269	<.001	<.001	3	1
BLOOD_Leukemia	OR1N2 →	+0.021	+4.705	.006	.003	3	1
BLOOD_Leukemia	MRGPRX3 →	+0.029	+4.409	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

AMELX by OR4C13 expression — BLOOD_Leukemia

Explore this box plot interactively →