OR4C12

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR4C12 mutation is significantly associated with the RNA expression of many other genes, with 3,577 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR4C12-associated genes across cancer lineages are RNU6-402P, TNPO3, and DHRS11. Each is linked with OR4C12 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR4C12-to-partner and partner-to-OR4C12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C12→partner) and Y-score (partner→OR4C12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRNU6-402P →+0.791+5.266<.001.00133
UCECTNPO3 →+0.328+1.769.007.00433
UCECDHRS11 →+0.559+3.491<.001.00233
SKCMCCDC93 →+0.440+1.851.002.00233
UCECC9orf78 →+0.339+2.526.001.00133
UCECSBDSP1 →+0.674+2.828<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,577 associations by consensus.

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