Across TCGA patient cohorts, OR4C12 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR4C12-associated genes across cancer lineages are ASNS, eIF4E, and 4E-BP1. Each is linked with OR4C12 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR4C12-to-partner and partner-to-OR4C12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C12→partner) and Y-score (partner→OR4C12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.430	+1.906	<.001	.015	3	3
UCEC	eIF4E →	+0.209	+1.662	.005	.011	2	3
UCEC	4E-BP1 →	+0.320	+3.584	<.001	.002	3	2
LUSC	TTF1 →	-0.604	-1.691	.045	.043	3	1
SKCM	LKB1 →	-0.091	-3.169	.038	.017	3	1
SKCM	p38-MAPK →	+0.145	+1.753	.027	.047	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

OR4C12 survival (RNA) · tumor vs normal (RNA) · all OR4C12 data types