Across TCGA cell cohorts, OR4C12 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. CNS shows the largest number of these associations.

The most reproducible OR4C12-associated genes across cancer lineages are SEL1L2, TLE7, and IRGC. Each is linked with OR4C12 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4C12-to-partner and partner-to-OR4C12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C12→partner) and Y-score (partner→OR4C12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	SEL1L2 →	+0.015	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	TLE7 →	+0.016	+5.643	<.001	.002	3	1
SKIN	IRGC →	+0.011	+3.196	.009	.007	3	1
LUNG_SCLC	IL3 →	+0.055	+5.029	<.001	.006	3	1
LUNG_SCLC	PRAMEF10 →	+1.180	+5.643	<.001	.002	3	1
LUNG_SCLC	PRAMEF17 →	+0.013	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Exploration

OR4C12 survival (RNA) · tumor vs normal (RNA) · all OR4C12 data types