Across TCGA patient cohorts, OR4A5 mutation is significantly associated with the RNA expression of many other genes, with 4,016 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR4A5-associated genes across cancer lineages are PIMREG, SSRP1, and RBM10. Each is linked with OR4A5 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR4A5-to-partner and partner-to-OR4A5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4A5→partner) and Y-score (partner→OR4A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PIMREG →	+1.018	+2.149	<.001	<.001	3	4
UCEC	SSRP1 →	+0.487	+3.839	.006	<.001	3	4
UCEC	RBM10 →	+0.323	+2.606	.002	<.001	3	4
LUAD	KIFC1 →	+0.871	+2.441	<.001	.001	3	4
LUAD	HJURP →	+0.919	+2.257	<.001	.005	3	4
UCEC	NUSAP1 →	+0.720	+2.354	.003	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,016 associations by consensus.

Exploration

OR4A5 survival (RNA) · tumor vs normal (RNA) · all OR4A5 data types