Across TCGA patient cohorts, OR4A5 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible OR4A5-associated genes across cancer lineages are Cyclin-B1, PI3K-p85, and ACC1. Each is linked with OR4A5 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR4A5-to-partner and partner-to-OR4A5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4A5→partner) and Y-score (partner→OR4A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.558	+1.807	.016	.027	3	3
SKCM	PI3K-p85 →	-0.168	-1.687	.027	.040	3	3
LUSC	ACC1 →	+0.523	+3.000	.012	.035	3	2
LUAD	EGFR →	-0.238	-1.906	.014	.016	3	2
LUAD	PKC-delta_pS664 →	-0.109	-1.987	.015	.029	3	2
LUAD	4E-BP1_pT37_T46 →	+0.361	+1.753	.012	.047	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration

OR4A5 survival (RNA) · tumor vs normal (RNA) · all OR4A5 data types