OR4A47

Across TCGA cell cohorts, OR4A47 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR4A47-associated genes across cancer lineages are FEZF2, OR7D4, and OR14I1. Each is linked with OR4A47 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4A47-to-partner and partner-to-OR4A47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FEZF2 grouped by OR4A47-low versus OR4A47-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4A47→partner) and Y-score (partner→OR4A47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FEZF2 →	+0.018	+4.273	<.001	.006	3	1
LARGE_INTESTINE	OR7D4 →	+0.019	+4.415	<.001	.007	3	1
LARGE_INTESTINE	OR14I1 →	+0.022	+4.415	<.001	.007	3	1
LARGE_INTESTINE	OR12D2 →	+0.082	+4.467	<.001	.004	3	1
SKIN	ADH4 →	+0.139	+4.095	<.001	.009	3	1
SKIN	MBD3L5 →	+0.024	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

FEZF2 by OR4A47 expression — LARGE_INTESTINE

Explore this box plot interactively →