OR2W3

Across TCGA cell cohorts, OR2W3 mutation is significantly associated with the RNA expression of many other genes, with 53 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR2W3-associated genes across cancer lineages are CSH1, IL17F, and TSPY4. Each is linked with OR2W3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2W3-to-partner and partner-to-OR2W3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CSH1 grouped by OR2W3-low versus OR2W3-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2W3→partner) and Y-score (partner→OR2W3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CSH1 →	+0.044	+2.665	<.001	.004	3	2
URINARY_TRACT	IL17F →	+0.056	+5.087	<.001	.004	3	1
PANCREAS	TSPY4 →	+0.037	+4.614	<.001	.004	3	1
BLOOD_Leukemia	EPPIN →	+0.006	+5.507	<.001	<.001	3	1
BLOOD_Leukemia	TSHB →	+0.261	+4.276	<.001	.007	3	1
BLOOD_Leukemia	OR9I1 →	+0.004	+4.539	.009	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

CSH1 by OR2W3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →