Across TCGA pan-cancer cohorts, OR2W2P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of OR2W2P’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where OR2W2P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR2W2P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

BRCA, HNSC, and KIRC are the cancer types where OR2W2P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR2W2P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	+0.052	<.001	4	view →
HNSC	All	III,IV	+0.023	.025	4	view →
KIRC	Female	All	+0.013	.041	2	view →
CHOL	All	All	+0.043	.024	1	view →
THCA	All	All	−0.015	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: OR2W2P RNA expression & survival · all OR2W2P data types