Q-omics provides the consensus-scored OR2W2P profile across patient tissues and cancer cell-line models. OR2W2P expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in UCEC. Among the 18 cancer types available for tumor–normal comparison, OR2W2P is differentially expressed in 5, with the highest sampling consensus in BRCA. Additionally, OR2W2P RNA expression shows 5,246 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight UCEC, BRCA, and TGCT as cancer lineages where OR2W2P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for OR2W2P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes OR2W2P survival associations across molecular data types. OR2W2P RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible OR2W2P RNA expression–survival associations across cancer types. High OR2W2P expression shows unfavorable associations in UCEC, COAD, ACC, ESCA, THCA and MESO. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCEC as the clearest survival context for OR2W2P RNA expression.
This table summarizes OR2W2P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for OR2W2P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. OR2W2P shows lower tumor expression in THCA and higher tumor expression in BRCA, HNSC, KIRC and CHOL. The BRCA box plot shows higher OR2W2P RNA expression in tumor versus normal tissue (log2 FC = +0.052, t-test p < 0.001).
This table shows molecular features associated with OR2W2P in patient tissues and cancer cell lines. In patient samples, OR2W2P shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
