Across TCGA patient cohorts, OR2W1 mutation is significantly associated with the RNA expression of many other genes, with 1,835 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2W1-associated genes across cancer lineages are UBL4A, SLC25A5P9, and LDLRAD4. Each is linked with OR2W1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2W1-to-partner and partner-to-OR2W1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2W1→partner) and Y-score (partner→OR2W1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	UBL4A →	+0.302	+2.038	.001	.004	3	3
LUSC	SLC25A5P9 →	+0.050	+3.036	<.001	.006	3	3
UCEC	LDLRAD4 →	-0.588	-2.678	.004	.006	3	2
UCEC	ZFAND2A →	+0.771	+3.343	<.001	.005	3	2
UCEC	TRO →	-1.197	-2.689	.003	.006	3	2
UCEC	SLC22A17 →	-1.002	-2.700	.004	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,835 associations by consensus.

Exploration

OR2W1 survival (RNA) · tumor vs normal (RNA) · all OR2W1 data types