Across TCGA patient cohorts, OR2W1 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2W1-associated genes across cancer lineages are Cyclin-B1, ASNS, and Acetyl-a-Tubulin-Lys40. Each is linked with OR2W1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2W1-to-partner and partner-to-OR2W1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2W1→partner) and Y-score (partner→OR2W1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.722	+2.459	.007	.020	3	3
SKCM	ASNS →	+0.342	+1.906	.022	.014	3	3
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.645	+3.584	.008	.002	3	2
UCEC	Src_pY527 →	-0.420	-2.990	.043	.036	3	2
SKCM	14-3-3_zeta →	+0.170	+1.874	.018	.049	3	2
SKCM	DJ-1 →	+0.173	+1.700	.005	.038	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Exploration

OR2W1 survival (RNA) · tumor vs normal (RNA) · all OR2W1 data types