Across TCGA patient cohorts, OR2T6 mutation is significantly associated with the RNA expression of many other genes, with 2,572 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2T6-associated genes across cancer lineages are NAE1, CLEC12A, and TRAJ12. Each is linked with OR2T6 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR2T6-to-partner and partner-to-OR2T6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T6→partner) and Y-score (partner→OR2T6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NAE1 →	+0.326	+2.771	.004	.002	3	4
SCLC	CLEC12A →	+2.226	+3.009	<.001	.003	3	3
GBM	TRAJ12 →	+0.637	+5.857	<.001	.002	3	3
UCEC	NDUFV1 →	+0.424	+2.738	.003	<.001	3	3
UCEC	POLD1 →	+0.514	+2.695	.006	<.001	3	3
UCEC	RAD54L →	+0.621	+2.823	.006	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,572 associations by consensus.

Exploration

OR2T6 survival (RNA) · tumor vs normal (RNA) · all OR2T6 data types