Across TCGA pan-cancer cohorts, OR2T6 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of OR2T6’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where OR2T6 RNA is repressed in tumor relative to normal tissue. In most cancer types OR2T6 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and PRAD are the cancer types where OR2T6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR2T6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.095	<.001	7	view →
KIRP	All	All	−0.065	<.001	7	view →
PRAD	All	All	−0.027	.038	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: OR2T6 RNA expression & survival · all OR2T6 data types