Across TCGA patient cohorts, OR2T6 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2T6-associated genes across cancer lineages are Rictor_pT1135, TIGAR, and MSH2. Each is linked with OR2T6 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2T6-to-partner and partner-to-OR2T6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T6→partner) and Y-score (partner→OR2T6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Rictor_pT1135 →	-0.132	-2.972	.010	.035	3	3
UCEC	TIGAR →	+0.146	+1.933	.017	.009	3	3
LUAD	MSH2 →	+0.378	+2.338	.003	.019	3	2
UCEC	Cyclin-B1 →	+0.819	+3.087	<.001	<.001	2	3
UCEC	p70-S6K_pT389 →	-0.225	-1.906	.003	.016	2	3
UCEC	PCNA →	+0.238	+3.584	.006	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Exploration

OR2T6 survival (RNA) · tumor vs normal (RNA) · all OR2T6 data types