Across TCGA cell cohorts, OR2T6 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR2T6-associated genes across cancer lineages are SLC17A1, GPR119, and KCNK16. Each is linked with OR2T6 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2T6-to-partner and partner-to-OR2T6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T6→partner) and Y-score (partner→OR2T6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	SLC17A1 →	+0.025	+3.099	<.001	.003	3	2
SKIN	GPR119 →	+0.024	+4.196	<.001	.002	3	1
SKIN	KCNK16 →	+0.036	+3.930	<.001	.003	3	1
LUNG_SCLC	SPINK4 →	+0.889	+2.869	.002	.008	3	1
LUNG_SCLC	CELA3A →	+0.093	+3.099	.003	.003	3	1
LUNG_SCLC	LCE5A →	+0.353	+3.099	.007	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Exploration

OR2T6 survival (RNA) · tumor vs normal (RNA) · all OR2T6 data types