Across TCGA patient cohorts, OR2T5 mutation is significantly associated with the RNA expression of many other genes, with 68 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR2T5-associated genes across cancer lineages are OR6C65, HNRNPCL3, and MIR6127. Each is linked with OR2T5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2T5-to-partner and partner-to-OR2T5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T5→partner) and Y-score (partner→OR2T5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OR6C65 →	+0.031	+5.797	<.001	.001	3	2
UCEC	HNRNPCL3 →	+0.073	+4.193	<.001	.001	3	1
SKCM	MIR6127 →	+0.227	+4.680	<.001	.007	3	1
SKCM	GNG10P1 →	+0.154	+5.624	<.001	.002	3	1
SKCM	MRPS18BP2 →	+0.079	+5.118	<.001	.001	3	1
SKCM	MTCO1P23 →	+0.088	+4.563	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

Exploration

OR2T5 survival (RNA) · tumor vs normal (RNA) · all OR2T5 data types