Across TCGA pan-cancer cohorts, OR2T35 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated OR2T35 data layer compared with 11 for mass-spec protein.
The strongest signal is observed in colon adenocarcinoma (COAD), where higher OR2T35 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR2T35 expression acts as an unfavorable survival marker.
COAD, LUAD, and SKCM are the cancer types where OR2T35 Mutation most reproducibly stratifies survival.
Mutation survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.