OR2T33

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR2T33 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. CNS shows the largest number of these associations.

The most reproducible OR2T33-associated genes across cancer lineages are CAMP, OLIG1, and VSTM2B. Each is linked with OR2T33 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2T33-to-partner and partner-to-OR2T33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CAMP grouped by OR2T33-low versus OR2T33-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T33→partner) and Y-score (partner→OR2T33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CNSCAMP →+0.621+3.602<.001.00631
CNSOLIG1 →+0.355+3.573<.001.00731
CNSVSTM2B →+0.475+3.584.001.00331
CNSTREML4 →+0.129+3.887<.001.00131
CNSCLPSL2 →+0.646+3.762<.001.00431
CNSCEACAM16 →+0.055+3.479<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

CAMP by OR2T33 expression — CNS

Box plot of CAMP in OR2T33-low vs OR2T33-high samples in CNS.

Explore this box plot interactively →

Exploration