OR2T33

Across TCGA cell cohorts, OR2T33 mutation is significantly associated with the mutation status of many other genes, with 1,056 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible OR2T33-associated genes across cancer lineages are SPEF2, NES, and PCDHB4. Each is linked with OR2T33 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR2T33-to-partner and partner-to-OR2T33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPEF2 grouped by OR2T33-low versus OR2T33-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T33→partner) and Y-score (partner→OR2T33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	SPEF2 →	+2.678	+3.652	.002	.002	1	4
SOFT_TISSUE	NES →	+4.502	+5.066	.007	.007	1	4
SOFT_TISSUE	PCDHB4 →	+4.502	+5.066	.007	.007	1	4
SOFT_TISSUE	TMEM132B →	+4.502	+5.066	.007	.007	1	4
SOFT_TISSUE	EGFLAM →	+5.502	+5.502	.003	.003	1	4
SOFT_TISSUE	PCDHB1 →	+5.502	+5.502	.003	.003	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,056 associations by consensus.

SPEF2 by OR2T33 expression — CNS

Explore this box plot interactively →