Across TCGA cell cohorts, OR2T2 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR2T2-associated genes across cancer lineages are OR8B8, C5orf52, and SIGLEC8. Each is linked with OR2T2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2T2-to-partner and partner-to-OR2T2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T2→partner) and Y-score (partner→OR2T2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OR8B8 →	+0.096	+4.321	<.001	.009	3	2
SKIN	C5orf52 →	+0.041	+5.415	<.001	.004	3	1
LUNG_NSCLC_LUAD	SIGLEC8 →	+0.013	+3.887	.002	.002	3	1
LUNG_NSCLC_LUAD	SCN2B →	+0.065	+4.405	<.001	.001	3	1
LUNG_NSCLC_LUAD	OR4X2 →	+0.014	+3.362	<.001	.007	3	1
LUNG_NSCLC_LUAD	OR1D2 →	+0.013	+4.266	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

OR2T2 survival (RNA) · tumor vs normal (RNA) · all OR2T2 data types